产品货号:
Z24787
中文名称:
PRKAR2A抗体
英文名称:
Anti-PRKAR2A Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PRKAR2A Antibody |
指标别名 | PKR2;PRKAR2;PRKAR2A |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | PRKAR2A |
抗体来源 | Rabbit |
抗体类型 | IgG |
计算分子量 | 46KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | Immunogen affinity purified |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | cAMP-dependent protein kinase type II-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR2A gene.cAMP is a signaling molecule important for a variety of cellular functions.cAMP exerts its effects by activating the cAMP-dependent protein kinase,which transduces the signal through phosphorylation of different target proteins.The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits.cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits.Four different regulatory subunits and three catalytic subunits have been identified in humans.The protein encoded by this gene is one of the regulatory subunits.This subunit can be phosphorylated by the activated catalytic subunit.It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase.This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). |
Uniprot ID | P13861 |
基因名全称 | cAMP-dependent protein kinase type II-alpha regulatory subunit |
推荐稀释比 | WB,1:500~1:2000 |
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